Two sample MR report
NEBL_Monocyte (Mono) against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | 0.1164739 | 0.0696465 | 0.2364206 |
| Weighted median | 4 | 0.0282224 | 0.0097648 | 0.0038499 |
| Inverse variance weighted | 4 | 0.0228007 | 0.0074284 | 0.0021449 |
| Simple mode | 4 | 0.0296472 | 0.0139455 | 0.1234857 |
| Weighted mode | 4 | 0.0296472 | 0.0137754 | 0.1204590 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.2700804 | 2 | 0.8736808 |
| Inverse variance weighted | 2.0998670 | 3 | 0.5519397 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.1168921 | 0.0864141 | 0.3087854 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 2.87e-05 | 0 | TRUE | 0.6140209 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
